Chemistry Faculty Members
His research interests at Colorado State will focus on the thermodynamics of nanoscale self-assembly processes in block copolymer composite materials and their applications in a variety of environments, including polymer-based photovoltaics, bio-enzymatic fuel cells, chemical and biological sensing devices, targeted chemical delivery, and hydrogel-based shape memory materials.
Conformation and potential energy surfaces of isolated and solvated non-rigid molecules, nucleation, growth, and structure of van der Waals clusters in the gas phase, energy dynamics and chemical reaction in van der Waals clusters, spectroscopy of reactive intermediates, metal oxide cluster catalysis
Intrinsically recyclable polymers; renewable monomers and sustainable polymers; precision (stereoselective, chemoselective & living) polymer synthesis; Lewis pair polymerization; new polymerization methodology; transition-metal, main-group & organic catalysis; biomass conversion to fuels, chemicals & materials.
Bioinorganic, Bioorganic, Physical Organic Chemistries, with focuses on characterization of menaquinone metabolism and ihibition of electron transport in tuberculosis bacteria, vanadium containing anti-diabetic and anti-malarial compounds, microemulsion drug-membrane interaction studies, copper (II) amyloid-beta and peptide complexation studies, and spectroscopic techniques including 1D and 2D NMR, EPR, fluorescence and IR.
Atmospheric chemistry; Instrument development & high resolution mass spectrometry; Field and laboratory measurements of reactive trace gases, pesticides and particles; Oxidation of organic compounds in the atmosphere; Biosphere-atmosphere exchange.
Plasma chemistry, reactivity of radicals with surfaces using LIF and molecular beam techniques. Plasma polymerization deposition and etching of materials. Characterization of plasma synthesized thin films.
Bioanalytical chemistry; environmental chemistry; chemical separations; microscale chemical instrumentation; capillary electrophoresis; biosensor development; paper-based analytical devices; microfluidics
Molecular recognition, self-assembly, development of novel biological recognition motifs, construction of synthetic receptors for small molecules of biological interest, design of catalytic peptides.
Dynamics of molecules and chemistry in the condensed phase, especially molecular assemblies, molecules in confined environments. Fundamental properties and processes governing cryopreservation.
Computational and Theoretical Chemistry
We employ computational and theoretical chemistry tools to study phenomena in Biology. In particular we are interested in how Biology achieves control of energy transduction and self-assembly. Protein-DNA complexes provide a nice set of basis set for such studies.
Prof. Menoni’s research bridges from material to optical sciences. She is engaged in the growth and characterization of high bandgap oxide materials for the engineering of interference coatings for high power lasers. She is also actively involved in using bright coherent beams of light of wavelengths between 10-50 nm for optics applications such as imaging and ablation.
New materials and methodologies involving solid-state and solution-phase reactions, particularly those involving kinetic control. We study structure/property relationships of materials (e.g., magnetism, electrical transport) using advanced synchrotron X-ray and time-of-flight neutron scattering and spectroscopic methods.
Predictions and designs of new reactions, reagents, and catalysts are tested through close collaboration with experiment. Guided by mechanistic investigation we develop tools to design more selective catalysts for asymmetric synthesis and renewable energy applications. Group members explore these areas using techniques in quantum chemistry, statistical modeling and data-mining alongside laboratory work.
Dr. Prasad's research is at the interface of the physical sciences and engineering with biology, using mathematical and computational methods as well as experiments. He teaches Transport Phenomena for Chemical Engineers (CBE 503) as well as a course in modeling methods in Systems and Synthetic Biology (BIOM 422).
Theoretical characterization of reaction mechanisms in homogeneous and heterogeneous catalysis, new electronic structure techniques, development of force fields or model potentials for chemical reactivity studies.
Atmospheric chemistry via studies in gas phase kinetics and photochemistry, heterogeneous chemistry, atmospheric field observations, and analyses of modeling results; Furthering understanding of the earth’s atmosphere, diagnosing, understanding of, and providing solutions to environmental issues of the stratospheric ozone depletion, air quality, and climate change; Provide new insights into gas phase chemical reactions, reactions on surfaces and in liquids, and photochemical processes; Developing new experimental methods both for laboratory studies and atmospheric measurements. file:///P:/adellet/Ravi/CV/Ravishankara-CV_Jan_2018.pdf
Multidisciplinary chemical design and fabrication of biomimetic materials for use in medical device applications. Research work includes: synthesis of organic and inorganic compounds including small-molecule therapeutics, polymers, and extended frameworks; analytical studies utilizing fluorescence, chemiluminesence, zeta potential, and LC/MS-TOF; fabrication and engineering of materials; biomedical efficacy and toxicity studies.
Organic and biological chemistry, new synthetic methodology, synthesis of chemically and biologically interesting natural products and study of their molecular mechanisms of action, study of enzymatic reaction mechanisms and development of therapeutic agents.
Coordination and organometallic complex synthesis and characterization: environmental control of spin-crossover properties; single-molecule magnets; solar photochemistry employing earth-abundant materials.
Computational design, simulation, and experimental validation of new enzymes, and crystalline biomolecular assemblies. We convert porous protein crystals into “3D molecular pegboards” for the controlled assembly of nanoparticles, enzymes, fluorescent proteins, oligonucleotides, and other functional molecules.
Fundamental and applied aspects of synthetic inorganic, analytical and environmental chemistry; fluorinated superweak ions; selective fluorination and chlorination of fullerenes; pollution prevention; infrared sensors for environmental and industrial applications; redox-cyclable ion-exchange; layered materials; metal carbonyls
Bioanalytical chemistry, single molecule detection and spectroscopy, laser spectroscopy, optical and scanning probe microscopy, optical biosensors for pharmaceutical and clinical chemistry.
Synthesis of natural products of biomedical significance and development of synthetic methodology for the construction of complex target molecules, design and synthesis of active site activated irreversible enzyme inhibitors, asymmetric synthesis of of alpha-amino acids, mechanism of action studies on anti-tumor drugs and antibiotics, oxidative cleavage and cross-linking of DNA, total synthesis and biogenesis of mycotoxic indole alkaloids from fungi, taxol biosynthesis, design and synthesis of antibiotics for drug-resistant microbial diseases, molecular biology and protein bioichemistry.