Melissa Reynolds

Melissa ReynoldsAssociate Professor of Chemistry and School of Biomedical Engineering, Associate Chair
Office: Chemistry B113C
Phone: 970-491-3775
Education: Ph.D., University of Michigan

Our research is multidisciplinary and focuses on the molecular design and fabrication of biomimetic materials for use in medical device applications. Depending on interests and expertise, group members are involved in a wide variety of research endeavors including:

  • synthesis of molecular, polymer, and extended framework biomaterials containing therapeutic functional groups
  • analytical and physical studies of biomaterials utilizing fluorescence, chemiluminesence, zeta potential, and LC/MS-TOF
  • fabrication and engineering of materials including spin-coating substrates and electrospinning nanofibers for tissue engineering
  • in vitro and in vivo efficacy and toxicity studies of biomaterials with potential translation to medical applications (preclinical studies done in collaboration with CSU Veterinary Medicine, UM Medical School, and Beaumont Research Hospital)
The group includes graduate and undergraduate students from the Department of Chemistry, Department of Biology, Department of Biomedical Sciences, and the School of Biomedical Engineering.  Chemistry graduate students represent all divisions in the department including analytical, organic, inorganic, physical, and materials.

Selected Publications

Damodaran, V. B.; Place, L. W.; Kipper, M. J.; Reynolds, M. M. Enzymatically Degradable Nitric Oxide Releasing Dextran Derivatives for Biomedical Applications. J. Mater. Chem. 2012, advance article. DOI: 10.1039/C2JM34834A

Wold, K. A.; Damodaran, V. B.; Suazo, L. A.; Bowen, R. A.; Reynolds, M. M. Fabrication of biodegradable polymeric nanofibers with covalently attached NO donors. ACS Appl. Mater. Interfaces. 2012, 4, 3022. DOI: 10.1021/am300383w

Damodaran, V. B.; Joslin, J. M.; Wold, K. A.; Lantvit, S. M.; Reynolds, M. M. S-Nitrosated biodegradable polymers for biomedical applications: synthesis, characterization and impact of thiol structure on the physicochemical properties.  J. Mater. Chem. 2012, 22, 5990-6001. DOI: 10.1039/C2JM16554F

Harding, J. L. and Reynolds, M. M. Metal Organic Frameworks as Nitric Oxide Catalysts. J. Am. Chem. Soc. 2012, article asap. DOI: 10.1021/ja210771m

Joslin, J. M. and Reynolds, M. M. Kinetics of S-nitrosation Processes in Aqueous Polymer Solution for Controlled Nitric Oxide Loading: Towards Tunable Biomaterials. ACS Appl. Mater. Interfaces 2012, article asap. DOI: 10.1021/am201807c

Joslin, J. M.; Damodaran, V. B.; Reynolds, M. M. Bio-Bandaids: A Natural Approach to Promoting Wound Healing. SurFACTS in Biomaterials 2012, 17, 1.

Damodaran, V. B.; Reynolds, M. M. Biodegradable S-Nitrosothiol Tethered Multiblock Polymer for Nitric Oxide Delivery. J. Mater. Chem. 2011, 21, 5870-5872. DOI: 10.1039/C1JM10315F

Reynolds, M. M. and Annich, G. A. The Non-Thrombogenic Endothelium. Organogenesis 2011, 7, 42-49. DOI: 10.4161/org.7.1.14029