Debbie Crans Professor

Office: Chemistry C307

Phone: (970) 491-7635

Website: http://wp.natsci.colostate.edu/crans

Education

  • Ph.D., Harvard University

About

My research is focused on bioinorganic, bioorganic, and physical organic chemistries. Our group is interested in the prominence of metals in medicine specifically vanadium and other transition metals and their ions. We utilize lipid and micro-emulsion interfaces to understand drug uptake across membranes. We study the coordination, speciation, and kinetic characterization of metal ion complexes with various biologically relevant ligands such as the amyloid-beta protein which is involved in Alzheimer’s disease. Projects involving menaquinone metabolism and ihibition of electron transport in tuberculosis bacteria are ongoing. We utilize various spectroscopic techniques in characterization of these systems including 1D and non-routine 2D NMR, EPR, UV-vis, fluorescence, and IR. The group has many CSU, US, and international collaborators.

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