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SUMMARY:Participant-Centric Sampling Tools for At-Home Blood and Saliva Col
 lection: Probing Personalized Longitudinal Responses
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20250129T160000
UID:2026-04-16-10-33-08@natsci.colostate.edu
DTSTAMP:20260416T103308
Description:About the Seminar:\n\nThis talk will highlight the development 
 of new platforms for self-collected/stabilized blood (homeRNA)\, saliva (C
 andyCollect)\, and air sampling. We have begun to envision and execute dec
 entralized clinical studies where data from study participants can be coll
 ected at timescales and locations that are not possible with traditional i
 n person clinical studies. Ongoing studies with homeRNA include investigat
 ing the immune response to wildfire smoke exposure\, infectious disease\, 
 and during treatment of rheumatologic diseases.  Notably we have captured
  immune response signatures during the elusive presymptomatic phase of res
 piratory infection drawing on the ability to take samples with high tempor
 al frequency (e.g.\, daily for ten days) afforded by at-home sampling. hom
 eRNA has also enabled recruitment and retention of underrepresented\, unde
 rserved\, and underreported (U3) populations\, overcoming barriers often e
 xperienced with conventional in-person research. Our CandyCollect device i
 s a lollipop-inspired open microfluidic saliva sampling system. I will sha
 re results of our initial studies in children with Group A streptococcal p
 haryngitis (strep throat)\, indicating that CandyCollect is effective and 
 is preferred by children and parents in comparison to traditional throat s
 wabs. CandyCollect also shows promise for salivary biomarker studies. Take
 n together\, remote self-sampling tools open up exciting new possibilities
  for clinical care and human subjects research.\n\nAbout the Speaker: \n\
 nAshleigh Theberge is Professor of Chemistry and Adjunct Professor of Urol
 ogy at the University of Washington. She holds a BA from Williams College 
 and a PhD from the University of Cambridge. Her group develops microscale 
 culture and analysis methods to study cell-cell\, cell-extracellular matri
 x\, and host-microbe interactions. She also develops new methods for at-ho
 me sampling and sample preservation for longitudinal studies including blo
 od\, saliva\, and air sampling. Selected awards include an NIH MIRA (2018\
 , 2023) and awards from the Beckman (2018)\, Packard (2019)\, Sloan (2021)
 \, and Dreyfus (2022) foundations. She co-Chaired the GRC on the Physics a
 nd Chemistry of Microfluidics in 2023. In 2024 she received a Schmidt Scie
 nce Polymath Award\, and she has received multiple awards for inclusive me
 ntoring.\n\n(Full bio here: https://depts.washington.edu/bcmelab/people/) 
 4:00 pm
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