BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//ZContent.net//ZapCalLib 1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
SUMMARY:Catalytic Transfer Reactions of Non-stabilized Carbenes
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20251020T160000
UID:2026-05-16-13-00-33@natsci.colostate.edu
DTSTAMP:20260516T130033
Description:About the seminar:\n\nCarbenes are versatile reactive intermedi
 ates that display orthogonal reactivity to common nucleophilic and electro
 philic functional groups. Catalytic carbene transfer reactions were first 
 discovered over a century ago\, and numerous examples of [n + 1]-cycloaddi
 tion reactions have since been developed\, often with control over diaster
 eo- and enanatioselectivity. Most of these reactions rely on the controlle
 d decomposition of diazoalkanes as a central strategy to access reactive c
 arbene equivalents.\n\nDespite the utility of diazoalkanes in organic synt
 hesis\, they are inherently limited by the need for stabilizing substituen
 ts such as aryl or carbonyl groups. In order to develop transfer reactions
  of nonstabilized carbenes\, it is necessary to consider an alternative se
 t of precursors. Our group has shown that nickel and cobalt catalysts can 
 promote reductive [n + 1]-cycloaddition reactions using readily available 
 and indefinitely stable 1\,1-dichloroalkanes and 1\,1-dichloroalkenes as p
 recusors for carbenes and vinylidenes\, respectively. In this seminar\, I 
 will describe our development of new cycloaddition methods and our current
  hypotheses about the mechanisms of these reactions.\n\nAbout the speaker:
 \n\nProfessor Christopher Uyeda is the Herbert C. Brown Professor of Chemi
 stry at Purdue University. After growing up in Vancouver\, Canada\, he att
 ended Columbia University\, where he earned his B.S. in biomedical enginee
 ring in 2005. As an undergraduate student\, Chris carried out research on 
 hydrophobically directed reactions with Prof. Ronald Breslow. Chris moved 
 to Harvard University to pursue graduate research under the guidance of Pr
 of. Eric Jacobsen. He obtained his Ph.D. in 2011\, and his thesis describe
 d the development of catalytic enantioselective Claisen rearrangements usi
 ng chiral hydrogen bond donors. Chris then carried out postdoctoral resear
 ch with Prof. Jonas Peters at Caltech as an NSF Center for Chemical Innova
 tion Fellow. His work involved studying molecular electrocatalysts for the
  production of solar fuels. In 2013\, Chris started his independent career
  at Purdue University as an assistant professor. In 2019\, he was promoted
  to associate professor with tenure and was promoted to full professor in 
 2022. Chris’s research program lies at the interface of organic and inor
 ganic chemistry\, and it focuses on the development of new catalytic react
 ions for the synthesis of fine chemicals\, pharmaceutical compounds\, poly
 mers\, and energetic materials. He is an associate editor for Science Adva
 nces and is the deputy director of the Department of Defense Energetic Mat
 erials Basic Research (EMBR) Center. 4:00 pm
END:VEVENT
END:VCALENDAR