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SUMMARY:Strain-Release Pentafluorosulfanylation: Strange Molecules Doing St
 ranger Things
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20250407T160000
UID:2026-04-30-20-35-35@natsci.colostate.edu
DTSTAMP:20260430T203535
Description:About the Seminar: \nThis presentation details recent progress
  in our laboratory toward the synthesis and evaluation of underemployed fl
 uorinated functional groups that have been made more accessible using the 
 TCICA/KF approach to oxidative fluorination. A major theme will be our rec
 ent merging of SF5 radical chemistry with strain-release functionalization
  of [1.1.1]propellane and [1.1.0]bicyclobutanes. Structural consequences o
 f making these SF5-based \"hybrid bioisosteres\" and preliminary mechanist
 ic insight will be discussed. Aside from being a topic of fundamental inte
 rest\, we believe this work affords an unusual and subtle type of flexibil
 ity in molecular design that could prove useful in increasing availability
  of building blocks containing C(sp3)–SF5 bonds to medicinal chemists\, 
 agrochemists\, and in the materials community.\n\nAbout the Speaker: \nPr
 of. Cody Ross Pitts received a B.S. in Chemistry with minors in Physics an
 d Musical Theatre from Monmouth University in 2010\, having conducted unde
 rgraduate research in organic chemistry with Prof. Massimiliano Lamberto. 
 In 2017\, he received his Ph.D. in Chemistry from Johns Hopkins University
  under the tutelage of Prof. Thomas Lectka\; his Ph.D. research was center
 ed on synthetic method development and physical organic chemistry\, includ
 ing development of radical fluorination chemistry and the first spectrosco
 pic observation of a stable fluoronium ion in solution. From 2017–2019\,
  Cody conducted research on inorganic fluorine chemistry with Prof. Antoni
 o Togni at ETH Zürich under an ETH Postdoctoral Fellowship. From 2019–2
 021\, Cody conducted research in total in synthesis with Prof. Phil S. Bar
 an at The Scripps Research Institute under an NIH Postdoctoral Fellowship.
  In July 2021\, Cody began his independent career at the University of Cal
 ifornia\, Davis\, and has established a research program that provides tra
 ining in reagent design\, method development\, mechanistic studies\, and o
 rganic synthesis. 4:00 pm
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