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SUMMARY:Molecular Adsorption and Transport at Living Cell Membranes Studied
  through Nonlinear Light Scattering and Microscopy
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20221117T160000
UID:2026-04-30-12-38-18@natsci.colostate.edu
DTSTAMP:20260430T123818
Description:About the Seminar\n\nNonlinear light scattering in the form of 
 Second Harmonic Generation\, due to its symmetry properties\, has been pro
 ven effective for observing molecular adsorption and transport at the surf
 aces of colloidal objects\, including living biological cells. This method
  affords membrane specificity\, real time resolution\, and the ability to 
 image single cells in examining molecule-membrane interactions.\n\nThis ta
 lk will lay out the basic principles of Second Harmonic Light Scattering (
 SHLS) and illustrate how SHLS can be applied to examine the surface of col
 loidal objects and molecular transport at cell membranes. This method has 
 been used to determine the fundamental mechanism of the century-old Gram s
 tain for classifying bacteria. Examples illustrating effects of molecular 
 structure and the membrane structure in influencing molecular adsorption a
 nd transport at living cell membranes will be presented. SHLS applied in t
 he imaging modality shows that molecular transport can be examined with sp
 atial resolution and that the transport rate varies greatly from regions t
 o regions at a cell membrane. Furthermore\, it will be shown that this sec
 ond harmonic microscopic tool can be used to determine membrane phase tran
 sition and membrane asymmetry.\n\n&nbsp\;\n\nAbout the Speaker \n\nHai-Lu
 ng Dai\, currently Laura Carnell Professor of Chemistry and Director of th
 e Institute for Membranes and Interfaces at Temple University\, was born i
 n 1954 in Taiwan and became a naturalized citizen of the US in 1993.\n\nA 
 graduate of National Taiwan University (1974)\, he holds a PhD from UC Ber
 keley (1981)\, and was a postdoctoral fellow at MIT (1981-84). In 1984 he 
 joined as assistant professor of chemistry at the University of Pennsylvan
 ia where he received tenure in 1989 and was promoted to full professor in 
 1992. From 1996-2002 he served as Chair of the Chemistry Department for tw
 o terms and later founded the Penn Science Teacher Institute. In 2002 he w
 as appointed the Hirschmann-Makineni Professor of Chemistry.\n\nIn 2007\, 
 Dai moved to Temple University as Dean of the College of Science and Techn
 ology\, a role he served till 2012. Since 2010\, Dai also assumed the resp
 onsibility of overseeing International Affairs. From 2012 to 2016\, Dai wa
 s Provost and Executive Vice President for Academic Affairs. From 2017 to 
 2022\, Dai continued his service as Vice President for International Affai
 rs.\n\nDai is an active\, funded researcher in physical chemistry and coll
 oidal and surface sciences. He has published &gt\;210 articles and deliver
 ed &gt\;360 invited lectures. His many honors include Guggenheim Fellowshi
 p\, Humboldt Fellowship from Germany\, the Coblentz Prize in Spectroscopy 
 (1990)\, the Ellis Lippincott Award from the Optical Society of America (2
 006)\, the Langmuir Lecturer Award in Colloid and Surface Chemistry of the
  American Chemical Society (2012)\; and named lectureships including the M
 orino Lectureship of Japan. He is a Fellow of both the American Chemical S
 ociety and American Physical Society and served as Chair of the APS Chemic
 al Physics Division. In 2019 the Journal of Physical Chemistry published a
  Festschrift honoring his contribution and leadership in chemistry. His ot
 her honors include a Distinguished Alum Award from National Taiwan Univers
 ity\, the Malone Award in International Education Leadership from the Asso
 ciation of Public and Land Grant Universities\, and a Knight Order of the 
 Star Medal from the government of Italy.\n\nIn addition to gubernatorial a
 ppointments in the Pennsylvania State Board on Drug\, Device and Cosmetic 
 in 2002-2006 and currently the Commission on Asian American Affairs\, Dai 
 has served to advise government agencies\, professional societies\, civic 
 organizations\, universities and research institutions around the world. H
 e has been a choral conductor since college and conducted many orchestral 
 concerts in the Academy of Music\, Kimmel Center\, and Temple Performing C
 enter in Philadelphia\, and the Beijing Concert Hall and the Shanghai City
  Hall. 4:00 pm
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