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SUMMARY:New Base-Promoted Oxidative and Reductive Coupling Reactions
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20230413T160000
UID:2026-04-18-14-28-47@natsci.colostate.edu
DTSTAMP:20260418T142847
Description:About the Seminar\n\nOur group’s overarching goal is to disco
 ver new concepts in base-promoted reactivity as a means to advance synthet
 ic chemistry. For example\, while base-promoted reactions typically accomp
 lish redox neutral transformations\, such as the addition of pronucleophil
 es to electrophiles\, we have identified general strategies for base-promo
 ted oxidative and reductive coupling reactions. This talk will discuss the
  development of these strategies in the context of two methods: the oxidat
 ive coupling of arenes with nucleophiles and the reductive defluorinative 
 coupling of trifluoromethylarenes with electrophiles. The mechanistic fram
 eworks of these methods will be compared to traditional base-promoted prot
 ocols to demonstrate unique capabilities and broad synthetic potential.\n\
 nAbout the Speaker \n\nJeff grew up in Saint Cloud\, MN and received his 
 B.A. from Saint John’s University in Collegeville\, MN in 2009. That yea
 r he began graduate studies with Tristan H. Lambert at Columbia University
 \, where his research focused on the use of aromatic ions as design elemen
 ts in catalysts\, reactions\, and polymeric materials. Upon receiving his 
 Ph.D. in 2014\, Jeff began postdoctoral studies with Stephen L. Buchwald a
 t Massachusetts Institute of Technology. At MIT\, he advanced the use of c
 opper catalysis for the enantioselective hydrofunctionalization of olefins
 . Jeff launched his independent research lab at Colorado State University 
 in 2017\, where his group is applying new concepts in acid-base chemistry 
 towards the development of new synthetic methods. Several of Jeff’s rece
 nt recognitions include a Cottrell Scholar Award and CSU’s College of Na
 tural Sciences Early Career Teaching and Mentoring Award. 4:00 pm
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