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SUMMARY:Predicting Chiral Catalysts: Selectivity and Generality in Asymmetr
 ic Catalysis
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20251110T160000
UID:2026-04-27-01-10-35@natsci.colostate.edu
DTSTAMP:20260427T011035
Description:About the seminar:\n\nIn this talk\, I will describe how we app
 ly a diverse set of machine learning algorithms to aid in the identificati
 on of optimal reaction conditions and general catalyst systems. A signific
 ant portion of this talk will focus on our experimental efforts in evaluat
 ing these tools for developing enantioselective reactions. Continuous impr
 ovement of this workflow has directed us to develop bespoke machine learni
 ng algorithms for top-down mechanistic analysis. These techniques will als
 o be covered and have been vetted in the complex organometallic space\, se
 rving as a useful complement to the traditional bottom-up approach. Finall
 y\, I will describe our latest efforts in developing novel catalyst struct
 ures and demonstrate their utility in various transformations.\n\nAbout th
 e speaker:\n\nJolene received her MSci in Chemistry from Queen\\'s Univer
 sity Belfast in 2013. She then pursued her PhD at the University of Cambri
 dge under the supervision of Professor Jonathan Goodman. After completing 
 her doctorate in 2017\, she was awarded a Marie Curie Postdoctoral Fellows
 hip and moved to the University of Utah to work with Professor Matthew Sig
 man. In September 2020\, Jolene joined the faculty at the University of 
 British Columbia as an Assistant Professor\, where her research focuses on
  the application of machine learning to organic synthesis. She was promote
 d to Associate Professor with tenure in July 2025. Jolene has received se
 veral awards for research excellence\, including the Thieme Chemistry Jour
 nals Award\, the Amgen Young Investigator Award\, the CSC Keith Fagnou Awa
 rd\, and the Brian James Prize for Catalysis Research in Canada. She was a
 lso selected as a Scialog Fellow in Automating Laboratories. Since launchi
 ng her independent research program\, she has published over 45 papers spa
 nning experimental chemistry\, computational methods\, artificial intellig
 ence\, drug delivery\, and more. 4:00 pm
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