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SUMMARY:RNAs in Protein Folding and Misfolding Disease, and Fun with Foldit
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20240229T160000
UID:2026-04-28-18-24-30@natsci.colostate.edu
DTSTAMP:20260428T182430
Description:About the Seminar:\n\nThe complexity of protein folding and unf
 olding in the cell is staggering\, and is affected by many factors. A majo
 r factor is the role of RNA as both a chaperone and aggregation-inducer. I
 n this seminar\, I will discuss our investigations into which RNAs are imp
 ortant\, what they are doing with regards to both protein folding and misf
 olding\, and how this impacts neurodegenerative disease and aging. We will
  conclude by discussing our work incorporating structural biology data and
  educational tools into the biochemistry citizen science video game Foldit
 .\n\nAbout the Speaker:\n\nScott Horowitz did his undergrad and masters at
  Wesleyan University\, and received his PhD from the University of Michiga
 n as a dual student in the labs of Raymond Trievel and Hashim Al-Hashimi s
 tudying the role of carbon-oxygen hydrogen bonding in methyl transfer. He 
 then moved the James Bardwell’s lab at Michigan and HHMI for his postdoc
 \, where he studied how chaperones help proteins fold. In 2017\, he starte
 d his own lab at The University of Denver studying primarily how nucleic a
 cids affect protein folding and aggregation. When not in lab\, Scott can o
 ften be found singing\, playing\, or listening to music. 4:00 pm
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