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SUMMARY:Immiscible Filtration Assisted by Surface Tension (IFAST) Systems f
 or Resource-Limited Bacterial Detection
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20211103T160000
UID:2026-04-19-01-01-22@natsci.colostate.edu
DTSTAMP:20260419T010122
Description:Literature Seminar:\n\nBacterial testing is extensively utilize
 d in the United States for health monitoring and preventative care. One si
 tuation in which it is particularly important is in the detection of Group
  B Streptococcus\, or GBS\, in pregnant individuals. GBS colonization duri
 ng pregnancy is particularly dangerous for both the mother and child\; it 
 is estimated that 130\,000 annual fetal &amp\; infant deaths are caused by
  preventable GBS disease. To combat this\, testing and subsequent antibiot
 ics are utilized to prevent GBS spread and infection. Unfortunately\, in m
 any lower-middle-income countries (LMIC)\, the GBS testing methodologies u
 tilized by non-LMIC countries are not viable due to resource limitations.Â
  To address this testing disparity\, easily accessible\, cheap\, and speci
 fic point-of-care assays for GBS are badly needed. Immiscible Filtration A
 ssisted by Surface Tension (IFAST) systems are a potential tool for addres
 sing this need. IFAST filtration leverages the interfacial energy present 
 between immiscible liquids\, allowing a single-step filtration and washing
  of bacteria captured by immunomagnetic microparticles. The microparticles
  with captured bacteria are magnetically drawn out of the aqueous solution
  and through the immiscible liquid interface\, leaving behind any unbound 
 material such as other bacteria\, the aqueous solution itself\, and other 
 matrix components. This results in a simple-to-conduct filtration and wash
 ing procedure\, opening the door for sensitive and specific immunoassays i
 n areas where a laboratory environment is inaccessible. 4:00 pm
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