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SUMMARY:A Fluorescent Sensor Array for Discrimination of Heavy Metal Ions u
 sing Host-Guest Chemistry
LOCATION:Chemistry A101
TZID:America/Denver
DTSTART:20190201T000000
UID:2026-04-23-07-22-53@natsci.colostate.edu
DTSTAMP:20260423T072253
Description:Literature Seminar\n\nHeavy metal detection has received signif
 icant attention in recent years due to the increasing risk to human health
  and surrounding ecosystems. Here\, the term heavy metal will encompass tr
 ansition and post transition metals. Heavy metals that pose concern can sp
 an from biologically relevant transition metals like copper and zinc\, to 
 post transition metals like lead and chromium\, to rare earth metals such 
 as lanthanides and actinides. To date\, there have been several reports of
  sensors that can quantitatively determine heavy metal concentrations in t
 he environment\, but those sensors can be rather limited in their applicat
 ion. Furthermore\, successful multiplexed detection of heavy metals normal
 ly requires the use of complex instrumentation like inductively coupled pl
 asma mass spectrometry. Other detection methods such as absorbance\, elect
 rochemistry\, and fluorescence have been explored to create low-cost\, eas
 y-to-use\, quantitative sensors but these typically detect single analytes
  with optimized reaction and coordination environments. This talk will foc
 us on the development of one of the first host-guest mediated fluorescent 
 arrays for multiplexed sensing of heavy metal ions. The use of fluorescenc
 e as the sensing mechanism allows for sensitive measurement while the host
 -guest supramolecular array permits multiplexed detection. The coordinatio
 n environment of the host permits binding of several metal ions while the 
 interactions of the guest in the cavity enables distinct fluorescent quant
 um yields\, dependent on an individual metal ion.\n\n(1) Liu\, Y.\; Mettry
 \, M.\; Gill\, A. D.\; Perez\, L.\; Zhong\, W.\; Hooley\, R. J. Selective 
 Heavy Element Sensing with a Simple Host–Guest Fluorescent Array. Anal. 
 Chem. 2017\, 89 (20)\, 11113–11121. https://doi.org/10.1021/acs.analchem
 .7b03377.\n\n&nbsp\; 4:00 pm
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