BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//ZContent.net//ZapCalLib 1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
BEGIN:VEVENT
SUMMARY:Emergent properties of membrane proximal signaling
LOCATION:Virtual Seminar
TZID:America/Denver
DTSTART:20210405T160000
UID:2026-04-30-16-23-34@natsci.colostate.edu
DTSTAMP:20260430T162334
Description:About the Seminar\n\nCritical for numerous cellular functions i
 s the dynamic interplay between cell surface receptors\, small GTPases\, a
 nd the enzymes that synthesize phosphatidylinositol phosphate (PIP) lipids
 . Using human neutrophils as a model system for cell polarity and migratio
 n\, we find that small GTPases and PIP lipid modifying enzymes trigger a m
 olecular signal that propagates across the plasma membrane in the form of 
 a traveling wave. This behavior\, termed excitability\, involves repetitiv
 e cycles of protein recruitment ON and OFF the membrane. My lab is current
 ly trying to decipher the molecular basis of the excitable signaling netwo
 rk using a combination of in vitro biochemistry\, genetics\, and live cell
  imaging. By unraveling how the excitable signaling network is regulated\,
  we aim to fill a gap in knowledge concerning how spatial patterning of bi
 ochemical reactions at the plasma membrane controls cell polarity and loco
 motion.\n\nZoom Link:TBA 4:00 pm
END:VEVENT
END:VCALENDAR