Intrinsically chiral inorganic nanotubes(NTs) based on WS2 and MoS2 are promising for visible-light absorbing materials for heterogeneous enantioselective photocatalysis and potentially for fundamental studies of the chiral induced spin selectivity (CISS) effect. Accurate identification of chiral handedness is essential for advancing enantioselective applications of these materials, but existing imaging and diffraction-based protocols do not rapidly facilitate the chiral properties of the outermost layer of the nanotube, especially for metal oxide core-inorganic shell structures that facilitate charge-carrier separation. This presentation will review the major methods people use to determine chirality, including handedness, and analyze their advantages and disadvantages. A new method based on the core-shell structure will be proposed.