Substituted heterocycles are prevalent in natural products, pharmaceuticals, and agrochemicals, especially those with sulfonyl-, sulfoxyl-, and alkyl-containing substituents. Due to their high oxidation potential and propensity for catalyst poisoning, the C(sp2)-H functionalization of N-heterocycles can be challenging. Pyridinium salts has been pivotal in recent light-promoted methods involving electron donor-acceptor (EDA) complexes, as they negate the […]

Please register to attend: https://www.research.colostate.edu/arc/seminars-workshops/ Teams link   Seminar Abstract: As thin films and coatings become increasingly central to advanced manufacturing, reliable, non-destructive characterization is essential for process control, product qualification, and failure analysis. This talk will review two highly practical X-ray techniques for thin film characterization: grazing-incidence X-ray diffraction (GIXRD) and X-ray reflectivity (XRR) on […]

Seminar Abstract: Cannabis sativa is a widely distributed plant with a lengthy history of attention by humanity. Despite this long-standing interest and the accompanying extensive use and consumption plus a substantial scholarly study, the broad and detailed chemistry of the plant and its chemical components are incompletely understood even by many of its modern practitioners. […]

Lithium salts have remained the gold standard pharmacological treatment for bipolar disorder for over seventy years, yet the mechanistic basis of their therapeutic action is unknown. A central barrier to mechanistic investigation is the absence of chemical tools capable of delivering Li+ with spatial and temporal precision — current dosing is systemic, providing no means […]

Seminar Abstract: Frustrated Radical Pairs (FRPs) are an emerging strategy for harnessing controlled single-electron reactivity via sterically or electronically mismatched donor-acceptor pairs. Unlike traditional two-electron Frustrated Lewis Pairs (FLPs), FRPs generate open-shell intermediates under mild, metal-free conditions. This creates new opportunities for selective bond formation. However, their use in carbon functionalization remains largely underexplored. This […]

Seminar Abstract: To address the plastics waste crisis, significant efforts have been directed towards the design and/or use of inherently recyclable polymers with competitive properties. However, industrial adoption of these materials remains challenging due to their expense and practicality. For this reason, in addition to the necessary mitigation of current plastic pollution, it is important […]

Seminar Abstract: Organosulfonium salts have recently seen an increase in utility as a handle towards a wide variety of powerful synthetic transformations. This is highlighted by the reactivity of thianthrenium salts and derivatives across transition-metal (TM) catalysis, photochemistry, electrochemistry, and radical polar crossover (RPC) reactions. Aryl sulfonium salt synthesis (e.g., thianthrenium and phenothiazinium species) has […]

Seminar Abstract: Amines are among the most prevalent functional group encountered in biologically active molecules and synthetic chemistry. Traditionally treated as synthetic end points, amines have recently emerged as valuable alkyl radical precursors. Central to these transformations is activation of the nitrogen center to reduce the Csp3–N bond dissociation energy. One activation strategy involves the […]