About the Seminar
Recently, we developed thermoplastic electrodes (TPEs) that are advantageous compared to traditional carbon composite electrodes in terms of cost, performance, and robustness. However, TPE applications in biosensing are currently limited due to a lack of facile methods for electrode modification. TPEs have a highly variable surface chemistry, lending to inconsistent immobilizations of biorecognition elements such as antibodies, aptamers, and enzymes. Cu(I)-catalyzed 1,3-dipolar cycloaddition (CuAAC), or Click Chemistry, has been demonstrated to be highly robust and adaptable to different surface chemistries. My work seeks to combine the benefits of both TPEs and CuAAC modifications to develop a customizable and versatile biosensing platform. Current results demonstrate the success of the modification of TPEs via CuAAC and strong potential for use as a viable biosensor assembly method.