His research interests at Colorado State will focus on the thermodynamics of nanoscale self-assembly processes in block copolymer composite materials and their applications in a variety of environments, including polymer-based photovoltaics, bio-enzymatic fuel cells, chemical and biological sensing devices, targeted chemical delivery, and hydrogel-based shape memory materials.
Polymer Science, Sustainable Chemistry, and Homogeneous Catalysis: Intrinsically recyclable & bio-derived sustainable polymers; chemical synthesis of biodegradable microbial plastics; precision (living and stereoselective & chemoselective) polymer synthesis; Lewis pair polymerization methodology for compounded sequence control; metal-catalyzed coordination polymerization for chiral polymers; organocatalysis for biomass conversion to fuels, chemicals & materials.
Bioinorganic, Bioorganic, Physical Organic Chemistries, with focuses on characterization of menaquinone metabolism and ihibition of electron transport in tuberculosis bacteria, vanadium containing anti-diabetic and anti-malarial compounds, microemulsion drug-membrane interaction studies, copper (II) amyloid-beta and peptide complexation studies, and spectroscopic techniques including 1D and 2D NMR, EPR, fluorescence and IR.
Molecular recognition, self-assembly, development of novel biological recognition motifs, construction of synthetic receptors for small molecules of biological interest, design of catalytic peptides.
Predictions and designs of new reactions, reagents, and catalysts are tested through close collaboration with experiment. Guided by mechanistic investigation we develop tools to design more selective catalysts for asymmetric synthesis and renewable energy applications. Group members explore these areas using techniques in quantum chemistry, statistical modeling and data-mining alongside laboratory work.
Organic and biological chemistry, new synthetic methodology, synthesis of chemically and biologically interesting natural products and study of their molecular mechanisms of action, study of enzymatic reaction mechanisms and development of therapeutic agents.