Zoom Link:
Topic: Sathyamoorthi Seminar
Time: Oct 24, 2022 04:00 PM Mountain Time (US and Canada)
Join Zoom Meeting
https://zoom.us/j/99146009571?pwd=SHJWOVNSZDVWUEJ5cllyQ3ZjUW4vZz09
Meeting ID: 991 4600 9571
Passcode: 102422
About the Seminar:
Advances in tethered olefin functionalization technology will greatly aid in the precise installation of alcohols and amines and in the efficient construction of stereochemical arrays. In such reactions, a nucleophilic auxiliary (“the tether”) is appended to ubiquitous functional groups, usually alcohols or amines, followed by a cyclization event. Because of geometric constraints on the transition states of intramolecular reactions, such cyclizations generally proceed with predictable regioselectivity and high diastereocontrol. In this presentation, I will describe my laboratory’s development of several classes of tethered olefin functionalization reactions and their applications to complex antibiotic synthesis.
About the Speaker:
Shyam Sathyamoorthi completed a B.S. degree in Cell and Molecular Biology with a minor in Chemistry at Tulane University, New Orleans, Louisiana, where he worked in the labs of Professor Ken Muneoka and Professor Robert A. Pascal, Jr. He then completed a PhD in chemistry at Stanford University under the guidance of Professor Richard N. Zare (2018) as well as a Doctor of Medicine degree at the Stanford University School of Medicine (2019). Since July 2019, he is an assistant professor in the Department of Medicinal Chemistry at the University of Kansas, Lawrence, KS, USA.