About the Seminar
Benefiting from an ever-expanding library of functionality, nanoscale ‘devices’ are being developed that can measure and manipulate their environment at molecular scales. Employed as platforms for wireless monitoring, I have used these devices to measure the nanoscale structure of folded DNA and RNA, enabling methods for remote observation DNA and RNA activity arising from intricate changes in 3D folded structure. Used as a therapeutic platform, I have used nanodevices to deliver and spatially track genetic payloads within living cells; enabling the development of improved gene-delivery systems. Currently, I am developing new classes of nanodevices that allow for the remote control of enzymes activity; enabling new avenues of therapeutic treatment. And most recently, preliminary work in the engineering of cells to spontaneously synthesize nanostructured materials is laying the foundation for nanoscale devices that can be generated within a living body, with precise composition and functionality.