Toward a general scheme to predict ionic liquid effects on biological molecules

Ionic liquids (ILs) have received significant attention in the past few decades as a novel class of materials with numerous proposed technological applications. ILs are salts that are liquid at the operating temperature; for room temperature operation this typically entails a large organic cation and a smaller anion. At the crux of their interesting behavior is the fact that they are typically polar and organic, so ILs can be selected with attributes of both aqueous and organic solvent environments. Despite all of the promise, there remain fundamental questions about the behavior of ILs. One particularly exciting area has been the use of ILs in biological systems. Recent publications from my and other groups have shown that ILs can have dramatic effects on protein structure and cell membrane permeability, but those effects are dependent on the specific system in consideration. My talk will review recent results and future plans to expedite the process of understanding these systems.

Division(s): Physical



Event Date: 06-01-2017

Event Time: 4:00 PM

Event Location: Chemistry A101

Mixer Time: 3:45 PM

Mixer Location: Chemistry B101E

Host: M. McCullagh